Technology
High-Pressure Chemistry
Leveraging Experience from Modeling to Manufacturing
API manufacturing often takes advantage of high pressure chemistry — those reactions involving a gas as a reagent such as catalytic hydrogenation. At Asymchem we’ve spent considerable time establishing a dedicated research team and building significant capacity at our two main API manufacturing sites to support this core technology. Our 300-3000L autoclaves are rated at 4-9 MPa, and are stainless steel and Hastelloy.
- Well equipped R&D facility with parallel screening equipment and bench-scale autoclaves
- Reaction modeling for efficient transfer to manufacturing scale
- Extensive and redundant large-scale manufacturing capacity
- Experience adapting batch high pressure processes to continuous flow
Services & Capacities
- Microscale experimental techniques (1-10 mg）
- Small-scale pilot simulation
- 48 vial Parallel screening
- 24 vial scaling-up screening ability
- Reaction kinetics measurement
- Small pilot workshop
- Full equipment kLa data set up, which maintains constant pressure automatically
- Automatic data collection (Hydrogen absorption kinetics can be realized)