Non-Precious Metal Catalysis (NPMC)

Cost-saving, Sustainable Alternatives for Coupling Reactions

The precious metals typically used as catalysts in pharmaceutical manufacturing — palladium, platinum, rhodium, and ruthenium — keep costs high and efficiencies low. Working in-house and in collaboration with industry and academic leaders, we have formed the NPMC Consortium to address these concerns. Working together we’ve developed processes and procedures that use non-precious metal catalysis (NPMC) to challenge cost, abundance, sustainability, and waste inefficiencies.

Asymchem NPMC Benefits

  • Active research into less expensive catalysts or enzymes for metal catalysis
  • Ni-catalyzed reductive coupling
  • Extends to heterocycles and functionalized alkyl halides